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Common side effects with dose escalation include nausea, vomiting, constipation, and reduced appetite, typically occurring most intensely for 1-2 weeks after each dose increase before tolerating improves

Evaluation of efficacy and safety of the glucagon receptor antagonist LY2409021 in patients with type 2 diabetes: 12- and 24-week phase 2 studies

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Acetyl-L-carnitine was safe and well-tolerated in most clinical trials

Centers for Disease Control and Prevention (CDC) 2024